Clinical Contributions

Perinatal Screening for Congenital Malformations and Genetic Disorders: Current Status and Future Directions.
Harold N Bass, MD; Jamie Beavers Taylor, BSc

This article provides a readable, concise overview of screening tests in newborn, infants and pregnant women. The field has made huge strides in recent decades, thanks in part to Kaiser Permanente efforts.
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West Meets East: A Kaiser Permanente Mid-Atlantic Experience in Providing Adolescent Health Care.
Ann L Komelasky, MSN, PNP; Carol Forster, MD

Permanente Medicine has long been in the forefront with respect to special clinics for teenagers. This account by a very committed health professional details some of this history, explains the workings of such facilities, and pleads for further development in this area.
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Stevens-Johnson Syndrome: A Case Study.
Matthew Smelik, MD

This is a single patient report and brief review of an always-interesting, treatable and not uncommon syndrome. It should serve as a reminder of its importance to clinicians.
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Corridor Consult: Is Ceftriaxone Useful in Management of Fever Without Focus?
Gary Burkhart, MD

This informal discussion of practical aspects of treatment of children with fever of unknown cause is the first of a series of brief overviews of common clinical situations by Kaiser Permanente experts.
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Evidence-Based Clinical Vignettes from the Care Management Institute: Major Depression.
David Price, MD, FAAFP

Based upon a recent revision of the Adult Depression Guideline by The Care Management Institute, this article succinctly summarizes major aspects of diagnosis, management and follow-up of this condition. Included is consideration of different cultural backgrounds, the elderly, and adolescent depression.
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The Relation Between Adverse Childhood Experiences and Adult Health: Turning Gold into Lead.
Vincent J Felitti, MD

This personal and passionate account of an important research initiative in Southern California presents convincing data showing a strong relation between emotional experiences as children and adult emotional and physical health.
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Dear Doctor
Anonymous

This single patient report is written by the patient. It personalizes the role of childhood experiences in production of illness and symptoms and drives home the point that physicians generally fail to recognize this common sequence.
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